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Man with male pattern baldness

Hair Loss Treatment

Male pattern hair loss, also called androgenetic alopecia, affects most men as they age, with up to half experiencing noticeable hair loss by age 50. Hair loss on the crown of the head is seen in 31% of men aged 40 - 55, and the prevalence increases to 53% by age 65. Women also lose hair as they age, as 50% will have female pattern baldness at some point in their lifetime.

Hair Loss Medications

While some hair loss is inevitable, there are treatments that can stimulate regrowth and slow progression. Available therapies are reviewed below.

  • Reference: Propecia prescribing information
Finasteride sexual side effects during the first year of treatment
Side effect Finasteride 1 mg
Decreased Libido 1.8% 1.3%
Erectile Dysfunction 1.3% 0.7%
Ejaculation disorder 1.2% 0.7%
Decreased volume of ejaculate 0.8% 0.4%
Stopped drug due to sexual side effects 1.2% 0.9%
  • Overall, 3.8% of finasteride-treated men reported ≥ 1 sexual adverse event compared to 2.1% of placebo-treated patients (p=0.04)
  • The incidence of sexual side effects did not increase with continued use up to 5 years
  • In a study of finasteride 1 mg daily in healthy men, a median decrease in ejaculate volume of 0.3 mL (-11%) compared with 0.2 mL (-8%) for placebo was observed after 48 weeks of treatment

  • Reference: Avodart prescribing information
Dutateride sexual side effects during the first six months of BPH treatment
Side effect Dutasteride 0.5 mg
Impotence 4.7% 1.7%
Decreased libido 3% 1.4%
Ejaculation disorder 1.4% 0.5%
  • The incidence of sexual side effects did not increase with continued use up to 2 years
  • In a 52-week study, dutasteride caused a mean reduction in total sperm count, semen volume, and sperm motility compared to placebo. Sperm concentration and sperm morphology were unaffected and mean values for all semen parameters remained within the normal range at all timepoints. The effects on total sperm count were not reversible after 24 weeks of follow-up.
man checking for hair loss in mirror

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